That wouldn’t work and would kill any hope of 2K having a future deal with the NFL. There was a show that aired on ESPN in 2003 that was just like that called Playmakers and ESPN had to cancel it because the NFL was scared that it would harm their image. They threatened to get rid of MNF. Even though the show was a fictional league with fictional teams and no references to the NFL. There’s a reason why it’s not available on any streaming services anywhere.
Because 2K signed that deal if they made any attempt to portray the league negatively it would kill any potential future games or contracts with the NFL.